SARS-CoV-2 3CLpro-IN-18 is a covalent inhibitor of the SARS-CoV-2 3CL protease, exhibiting potent enzymatic inhibition (IC50 = 0.478 µM) and antiviral activity in Vero E6 cells (EC50 = 2.499 µM) with low cytotoxicity. This compound is a valuable research tool for studying coronavirus replication and for the development of antiviral therapeutics in both biochemical and cellular assays.
Molekulargewicht:
328.82
Formel:
C17H13ClN2OS
Target-Kategorie:
SARS-CoV
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