VEGFR-2-IN-36 (compound 15) is a potent VEGFR-2 inhibitor with an IC50 value of 0.067 µM and acts as an apoptosis inducer with demonstrated anticancer efficacy, modulating apoptotic pathways by upregulating BAX and downregulating Bcl-2, leading to cytotoxic effects on cancer cell lines, including MCF-7 (IC50 = 0.42 µM) and HepG2 (IC50 = 0.22 µM).
Molekulargewicht:
489.48
Formel:
C24H23N7O5
Target-Kategorie:
VEGFR
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