RIPK2/3-IN-1 is a potent inhibitor of both RIPK2 and RIPK3 kinases, exhibiting IC50 values of 3 nM for RIPK2 and 117 nM for RIPK3. Additionally, in a 14-TriLAN-Gly/NOD1 THP-1 cell-based NF-kappaB reporter assay, RIPK2/3-IN-1 demonstrates an IC50 value of 14 4 nM against RIPK2.
Molekulargewicht:
456.54
Formel:
C24H16N4O2S2
Target-Kategorie:
RIP kinase
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