SJ1008030 (compound 8) formic is a potent and selective PROTAC-based JAK2 degrader. It demonstrates strong anti-proliferative activity in vitro against MHH-CALL-4 leukemia cells with an IC50 of 5.4 nM, supporting its application in hematological cancer research.
Molekulargewicht:
919.96
Formel:
C43H45N13O9S
Target-Kategorie:
JAK,PROTACs
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