JPS014 TFA is a VHL-based PROTAC that selectively degrades HDAC1/2. This degradation leads to transcriptional changes and induces apoptosis in cellular models like HCT116, supporting its use in oncology research for probing HDAC function and targeted protein degradation.
Molekulargewicht:
968.09
Formel:
C48H60F3N7O9S
Target-Kategorie:
Apoptosis,HDAC,PROTACs
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