SN38-COOH is the active metabolite of irinotecan, a topoisomerase I inhibitor that blocks DNA and RNA synthesis. It is a key payload for constructing antibody-drug conjugates (ADCs) and is widely used in cancer research for both in vitro cytotoxicity assays and in vivo efficacy studies.
Molekulargewicht:
492.48
CAS Nummer:
[2170118-23-5]
Formel:
C26H24N2O8
Target-Kategorie:
Drug-Linker Conjugates for ADC
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