This phosphoramidite reagent, featuring a constrained ethyl (cEt) locked nucleic acid (LNA) backbone and a 5-methyluridine (m5U) base, is designed for oligonucleotide synthesis. Its resulting antisense oligonucleotides demonstrate potent gene silencing activity and a favorable safety profile in both cellular and animal studies, supporting therapeutic discovery research.
Molekulargewicht:
786.85
CAS Nummer:
[1197033-22-9]
Formel:
C42H51N4O9P
Target-Kategorie:
Others,Nucleoside Antimetabolite/Analog
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