LU-005i is a potent and selective small molecule inhibitor of the immunoproteasome subunit beta5i (IC50 = 6.6 nM), showing >40-fold selectivity over the constitutive proteasome subunit beta5c. This inhibitor is a valuable research tool for studying immunoproteasome function in autoimmune disease and cancer models, both in vitro and in vivo.
Molekulargewicht:
586.72
CAS Nummer:
[1620107-33-6]
Formel:
C31H46N4O7
Target-Kategorie:
Proteasome,Others
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