DBCO-PEG4-GGFG-Dxd is a cleavable linker-payload conjugate for constructing antibody-drug conjugates (ADCs). Its DBCO group enables efficient bioconjugation via click chemistry with azide-modified antibodies, delivering the topoisomerase I inhibitor Dxd to target cells. This construct is utilized in oncology research for evaluating potent antitumor activity in both in vitro and in vivo models.
Molekulargewicht:
1375.45
Reinheit:
96.58% (May vary between batches)
CAS Nummer:
[2694856-51-2]
Formel:
C72H79FN10O17
Target-Kategorie:
Drug-Linker Conjugates for ADC
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