NPBA is a dual-function small molecule that acts as a TASK-3 (KCNK9) channel agonist and a TWIK2 channel blocker. This activity enables it to potently suppress NLRP3 inflammasome activation in macrophages, making it a valuable research tool for studying inflammation and potassium channel biology in both cellular and animal models.
Molekulargewicht:
353.3
CAS Nummer:
[524033-40-7]
Formel:
C16H14F3N3O3
Target-Kategorie:
Potassium Channel,Others
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