PF-1163A is a fungal depsipeptide that selectively inhibits the ERG25p C-4 methyl oxidase, disrupting ergosterol biosynthesis. It demonstrates antifungal activity against specific strains like Candida albicans and can synergize with fluconazole against resistant isolates, making it a valuable tool for studying fungal sterol metabolism and combination therapies in vitro.
Molekulargewicht:
477.6
CAS Nummer:
[258871-59-9]
Formel:
C27H43NO6
Target-Kategorie:
Others,Antifungal
* Mehrwertsteuer und Versandkosten nicht enthalten. Irrtümer und Preisänderungen vorbehalten