AB-161 is an orally bioavailable small molecule that destabilizes HBV RNA and inhibits PAPD5/7, primarily acting in the liver. It potently reduces hepatitis B surface antigen (HBsAg) levels with an EC50 of 2.2 nM and is used in research for investigating HBV infection, including in vitro and in vivo studies.
Molekulargewicht:
433.41
CAS Nummer:
[2848560-66-5]
Formel:
C21H21F2N3O5
Target-Kategorie:
HBV
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