IQ-1S is a potent small molecule inhibitor of NF-kappaB and AP-1 signaling pathways, with an IC50 of 1.8 µM. It functions by binding with high affinity to JNK isoforms, particularly JNK3 (Kd 87 nM), making it a valuable tool for studying inflammation, apoptosis, and neuronal death in cellular and animal models.
Molekulargewicht:
269.23
CAS Nummer:
[1421610-21-0]
Formel:
C15H8N3NaO
Target-Kategorie:
JNK
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