LH10 is a potent fexaramine-based FXR agonist (EC50 = 0.14 µM). It demonstrates hepatoprotective efficacy in preclinical models, including ANIT-induced cholestasis, APAP-induced acute liver injury, and non-alcoholic steatohepatitis (NASH), supporting research into metabolic and liver diseases.
Molekulargewicht:
515.64
Formel:
C34H33N3O2
Target-Kategorie:
FXR
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