SPA107 (Hemiasterlin methyl ester) is a potent antimitotic agent that inhibits tubulin polymerization with an IC50 of 0.5 nM. It demonstrates significant cytotoxicity against p53-mutated MCF-7 breast cancer cells at the same potency, making it a valuable tool for studying cytoskeleton dynamics and cancer therapeutics in vitro.
Molekulargewicht:
540.74
CAS Nummer:
[179939-69-6]
Formel:
C31H48N4O4
Target-Kategorie:
Microtubule Associated,Others
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