ANO1-IN-4 (Compound 10bm) is a potent and reversible TMEM16A (ANO1) channel inhibitor with an IC50 of 30 nM. It exhibits metabolic stability and has been shown to suppress spontaneous ileal contractions ex vivo, making it a useful research tool for studying gastrointestinal motility and calcium-activated chloride channel physiology.
Molekulargewicht:
457.33
CAS Nummer:
[2098490-06-1]
Formel:
C19H19BrF2N2O2S
Target-Kategorie:
Chloride channel
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