UKH-1114 is a potent and selective sigma2 receptor/Tmem97 agonist (Ki = 46 nM) with demonstrated antinociceptive efficacy. It effectively reverses nerve injury-induced mechanical hypersensitivity in murine models without motor deficits, making it a valuable research tool for investigating neuropathic pain mechanisms in both in vitro and in vivo studies.
Molekulargewicht:
375.43
CAS Nummer:
[2113664-14-3]
Formel:
C22H24F3NO
Target-Kategorie:
Sigma receptor
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