PDE1-IN-9 (7a) is a potent and selective PDE1C inhibitor (IC50 = 11 nM) that suppresses pro-inflammatory cytokine expression and reduces NO and ROS production. It exhibits good metabolic stability and is a valuable research tool for studying PDE1-related pathways in inflammatory and oxidative stress models, both in vitro and in vivo.
Molekulargewicht:
441.57
CAS Nummer:
[2982945-41-3]
Formel:
C28H31N3O2
Target-Kategorie:
NO Synthase,PDE
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