c-Myc inhibitor15 (Compound A5) is a selective small molecule that disrupts c-Myc/Max interaction, inducing c-Myc degradation and apoptosis. It shows cytotoxic activity in A549 and NCI-H1299 lung cancer cells and demonstrated significant tumor growth inhibition in an allogeneic in vivo model, supporting research into c-Myc-driven cancers.
Molekulargewicht:
457.57
Formel:
C27H31N5O2
Target-Kategorie:
c-Myc,Apoptosis
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