PSB-22269 is a potent GPR17 antagonist (Ki = 8.91 nM) that inhibits cAMP signaling and G protein activation. Its binding involves key arginine residues and a hydrophobic pocket. This compound promotes myelin regeneration in preclinical studies, making it a valuable tool for researching multiple sclerosis and other demyelinating diseases.
Molekulargewicht:
443.45
Formel:
C26H21NO6
Target-Kategorie:
Orphan Receptor,Others
* Mehrwertsteuer und Versandkosten nicht enthalten. Irrtümer und Preisänderungen vorbehalten
