HP211206 is a PROTAC-based degrader of SARS-CoV-2 Mpro (main protease), including resistant mutants, with an IC50 of 181.9 nM and a DC50 of 621 nM. It demonstrates antiviral activity and serves as a valuable chemical tool for studying coronavirus protease function and degradation mechanisms in both in vitro and cellular research.
Molekulargewicht:
883.94
Formel:
C42H55F2N9O10
Target-Kategorie:
Virus Protease,PROTACs,SARS-CoV
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