Fibrostat (Compound 5n) is a potent and selective HDAC6 inhibitor (IC50 = 63 nM) with demonstrated antifibrotic activity. It reduces fibronectin and collagen I expression in vitro and shows efficacy in models like perfused rat hearts and zebrafish larvae, supporting its use in fibrosis research.
Molekulargewicht:
484.59
Formel:
C29H32N4O3
Target-Kategorie:
HDAC
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