GDC-0134 is a brain-penetrant, small-molecule inhibitor of dual leucine zipper kinase (DLK) that blocks downstream JNK activation to prevent neuronal degeneration. It is utilized in preclinical research for neurodegenerative diseases like ALS, with studies demonstrating neuroprotective effects in both cellular and animal models.
Molekulargewicht:
440.4
CAS Nummer:
[1637394-01-4]
Formel:
C19H20F4N6O2
Target-Kategorie:
JNK
* Mehrwertsteuer und Versandkosten nicht enthalten. Irrtümer und Preisänderungen vorbehalten
