Desonide (Standard), CAS [[638-94-8]] Preis auf Anfrage

Artikelnummer: BYT-ORB3025703
Artikelname: Desonide (Standard), CAS [[638-94-8]] Preis auf Anfrage
Artikelnummer: BYT-ORB3025703
Hersteller Artikelnummer: orb3025703
Alternativnummer: BYT-ORB3025703-10
Hersteller: Biorbyt
Kategorie: Biochemikalien
Desonide (Standard) is the standard substance of Desonide, and it is applicable for quantitative analysis, quality control, and related research in biochemical experiments. Desonide (Prednacinolone) is a synthetic glucocorticosteroid for topical use, with anti-inflammatory activity. Desonide binds to glucocorticoid receptors in the cytoplasm, and the ligand-receptor complex is translocated as a homodimer into the nucleus, where transcription activation via glucocorticoid response elements within glucocorticoid-responsive genes occur. This agent induces transcription of genes coding for anti-inflammatory proteins, including lipocortin-1, interleukin-10, interleukin-1 receptor antagonist and neutral endopeptidase. Increased synthesis of lipocortin-1 has an inhibitory effect on phospholipase A2, which in turn inhibits the release of arachidonic acid, thereby controlling the biosynthesis of potent mediators of inflammation such as prostaglandins and leukotrienes.
Molekulargewicht: 416.51
CAS Nummer: [638-94-8]
Formel: C24H32O6
Target-Kategorie: Glucocorticoid Receptor