SB334867 HCl, CAS [[249889-64-3]] Preis auf Anfrage

Produktübersicht

• Artikelname: SB334867 HCl, CAS [[249889-64-3]] Preis auf Anfrage
• Artikelnummer: BYT-ORB3027303
• Hersteller Artikelnummer: orb3027303
• Alternativnummer: BYT-ORB3027303-100, BYT-ORB3027303-5, BYT-ORB3027303-50
• Hersteller: Biorbyt
• Kategorie: Biochemikalien

Produktbeschreibung

SB-334867 (SB 334867A) is a potent, selective, and blood-brain barrier permeable antagonist of the orexin-1 (OX1) receptor, demonstrating significant selectivity against OX2 (pKb=7.4), and exhibiting 100-fold selectivity over 5-HT2B and 5-HT2C, with pKi values of 5.4 and 5.3, respectively. This compound effectively reduces ethanol consumption and obstructs the development of morphine-induced sensitization to locomotor activity in vivo.

Produkteigenschaften

• Molekulargewicht: 355.78
• CAS Nummer: [249889-64-3]
• Formel: C17H14ClN5O2
• Target-Kategorie: OX Receptor