RS47 (Compound 1a) is a small molecule (Kd = 1.1 µM) that specifically targets RelB, selectively inhibiting the non-canonical NF-kappaB pathway by disrupting RelB binding to target DNA. It exhibits antitumour activity in vivo and in vitro and may be used in studies of colorectal cancer and B-cell lymphoma.
Molekulargewicht:
354.43
Reinheit:
98.76% (May vary between batches)
CAS Nummer:
[301655-16-3]
Formel:
C18H18N4O2S
Target-Kategorie:
NF-kappaB,Others
Anwendungsbeschreibung:
Solubility: DMSO:20 mg/mL (56.43 mM)
* Mehrwertsteuer und Versandkosten nicht enthalten. Irrtümer und Preisänderungen vorbehalten