BBI-355 is an oral, potent, and selective small molecule CHK1 inhibitor with an IC50 of 0.3 nM. It exhibits significant antitumor activity, both as a monotherapy and in combination with targeted therapies, across various ecDNA+ oncogene-amplified tumor models.
Molekulargewicht:
377.40
CAS Nummer:
[2871056-82-3]
Formel:
C19H19N7O2
Target-Kategorie:
Chk
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