BKT-300 is a potent and selective inhibitor of Protein regulator of cytokinesis 1 (PRC1), with a Kd value of 28.3 nM. It disrupts microtubule architecture, induces G2/M phase arrest, mitotic catastrophe, and caspase-3-dependent apoptosis, presenting potential as a novel therapy for advanced acute myeloid leukemia (AML).
Molekulargewicht:
399.44
CAS Nummer:
[2551033-16-8]
Formel:
C22H25NO6
Target-Kategorie:
Others
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