PROTAC STING degrader-4 Preis auf Anfrage

Produktübersicht

• Artikelname: PROTAC STING degrader-4 Preis auf Anfrage
• Artikelnummer: BYT-ORB3027573
• Hersteller Artikelnummer: orb3027573
• Alternativnummer: BYT-ORB3027573-10, BYT-ORB3027573-50
• Hersteller: Biorbyt
• Kategorie: Biochemikalien

Produktbeschreibung

PROTACSTING degrader-4 is a covalent STINGPROTAC degrader free of nitro groups, exhibiting a DC50 of 3.23 µM. It effectively inhibits STING and its downstream signaling pathways, including p-TBK1 and p-NF-kappaB (p-P65), as well as immune-inflammatory cytokines. Additionally, PROTACSTING degrader-4 mitigates renal and blood inflammation in mouse models of Cisplatin-induced acute kidney injury (AKI).

Produkteigenschaften

• Formel: C39H42Cl2N8O9
• Target-Kategorie: NF-kappaB,IkappaB/IKK,PROTACs,STING