PDEdelta/NAMPT IN-1, CAS [[2976498-55-0]] Preis auf Anfrage

Produktübersicht

• Artikelname: PDEdelta/NAMPT IN-1, CAS [[2976498-55-0]] Preis auf Anfrage
• Artikelnummer: BYT-ORB3027604
• Hersteller Artikelnummer: orb3027604
• Alternativnummer: BYT-ORB3027604-10, BYT-ORB3027604-50
• Hersteller: Biorbyt
• Kategorie: Biochemikalien

Produktbeschreibung

PDEdelta/NAMPT IN-1 (Compound 17d) is a dual inhibitor targeting phosphodiesterase 6 (PDE6) with a dissociation constant (KD) of 0.410 nM and nicotinamide phosphoribosyltransferase (NAMPT) with an inhibitory concentration (IC50) of 2.21 nM. It disrupts KRAS-related signaling by inhibiting NAMPTs role in the synthesis of nicotinamide adenine dinucleotide (NAD+), consequently inducing apoptosis in pancreatic cancer cells with KRAS mutations. This compound holds potential for research in KRAS-mutant pancreatic cancer.

Produkteigenschaften

• Molekulargewicht: 494.61
• CAS Nummer: [2976498-55-0]
• Formel: C26H30N4O4S
• Target-Kategorie: PDE,NAMPT,Kras,Ras,Apoptosis