Cbz-(S,S)-Pro-Pro-allyl (compound 1a) is a dual inhibitor of cyclooxygenase-2 and 5-lipoxygenase, with IC50 values of 0.146 nM, 0.003 nM, and 0.64 nM for COX-1, COX-2, and 5-LOX, respectively. Additionally, Cbz-(S,S)-Pro-Pro-allyl exhibits anti-inflammatory properties.
Formel:
C21H26N2O5
Target-Kategorie:
COX,Lipoxygenase
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