GSK3-IN-10 (Compound 4) is a multi-target inhibitor primarily affecting GSK3alpha and GSK3beta with IC50 values of 1.0 nM and 2.0 nM, respectively. It inhibits the activation of beta-catenin, enhances neuronal survival, and provides protective effects against endoplasmic reticulum stress.
Molekulargewicht:
364.347
CAS Nummer:
[844441-56-1]
Formel:
C17H18F2N4O3
Target-Kategorie:
CDK,Others,DYRK,GSK-3,JNK,Wnt/beta-catenin
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