AMPK-IN-5 (compound 7m) is a derivative of osthole that inhibits MAPK signaling by blocking the phosphorylation of JNK and p38, thereby suppressing the release of inflammatory cytokines. AMPK-IN-5 can reduce ulcerative colitis induced by dextran sulfate sodium and acute lung injury induced by LPS.
Formel:
C24H34N2O4
Target-Kategorie:
JAK,p38 MAPK
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