AurkA allosteric-IN-1 Preis auf Anfrage

Produktübersicht

• Artikelname: AurkA allosteric-IN-1 Preis auf Anfrage
• Artikelnummer: BYT-ORB3133930
• Hersteller Artikelnummer: orb3133930
• Alternativnummer: BYT-ORB3133930-10,BYT-ORB3133930-50
• Hersteller: Biorbyt
• Kategorie: Biochemikalien

Produktbeschreibung

AurkA allosteric-IN-1 (compound 6h) is an Aurora A (AurkA) inhibitor with an IC50 of 6.50 µM, which inhibits both the catalytic and non-catalytic activities of Aurora A. Aurora A is involved in the regulation of bipolar mitotic spindle assembly and the fidelity of chromosome segregation during mitosis. AurkA allosteric-IN-1 interferes with Aurora A by binding to the Y-pocket, thereby preventing its interaction with the activator TPX2.

Produkteigenschaften

• Formel: C20H16N2O3
• Target-Kategorie: Aurora Kinase