NLRP3-IN-33 (Compound 12o) is an inhibitor of AChE and BChE capable of crossing the blood-brain barrier, with IC50 values for hAChE and hBChE at 1.02 µM and 7.03 µM, respectively. NLRP3-IN-33 exhibits antioxidant, anti-inflammatory, and metal chelating activities, making it a candidate for Alzheimers disease (AD) research.
Formel:
C21H19N3O5
Target-Kategorie:
Cholinesterase (ChE),Reactive Oxygen Species
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