ASX-173, CAS [[2748800-08-8]] Preis auf Anfrage

Produktübersicht

• Artikelname: ASX-173, CAS [[2748800-08-8]] Preis auf Anfrage
• Artikelnummer: BYT-ORB3136213
• Hersteller Artikelnummer: orb3136213
• Alternativnummer: BYT-ORB3136213-10, BYT-ORB3136213-50
• Hersteller: Biorbyt
• Kategorie: Biochemikalien

Produktbeschreibung

ASX-173 is an orally active asparagine synthetase (ASNS) inhibitor with an IC50 of 0.113 µM and a Ki of 0.4 nM. It enhances the anticancer activity of L-Asparaginase (ASNase). When combined with ASNase, ASX-173 disrupts nucleotide synthesis and induces cell cycle arrest, apoptosis (apoptosis), and autophagy (autophagy) in leukemia cells. This combination also slows the growth of OCI-AML2 xenograft tumors. ASX-173 is applicable in research on acute lymphoblastic leukemia, acute myeloid leukemia, colorectal cancer, and other cancers.

Produkteigenschaften

• Molekulargewicht: 475.56
• CAS Nummer: [2748800-08-8]
• Formel: C28H30FN3O3
• Target-Kategorie: Autophagy,CDK,PARP,Akt,ATG,Apoptosis,Caspase