RG-239, CAS [[1199222-56-4]] Preis auf Anfrage

Artikelnummer: BYT-ORB3136216
Artikelname: RG-239, CAS [[1199222-56-4]] Preis auf Anfrage
Artikelnummer: BYT-ORB3136216
Hersteller Artikelnummer: orb3136216
Alternativnummer: BYT-ORB3136216-10, BYT-ORB3136216-50
Hersteller: Biorbyt
Kategorie: Biochemikalien
RG-239 is an orally active TGR5 agonist with an EC50 of 120 nM, significantly more potent than Betulinic acid (EC50= 1.04 µM). It exhibits much higher selectivity for TGR5 over FXRalpha. The compound enhances mitochondrial activity in adipocytes and promotes neurite outgrowth at higher concentrations. Additionally, RG-239 inhibits LPS-induced iNOS expression and nitrite production in Raw264.7 cells and microglia. RG-239 is applicable for research related to type 2 diabetes.
Molekulargewicht: 496.76
CAS Nummer: [1199222-56-4]
Formel: C33H52O3
Target-Kategorie: GPCR19