VS1150, CAS [[2855238-97-8]] Preis auf Anfrage

Produktübersicht

• Artikelname: VS1150, CAS [[2855238-97-8]] Preis auf Anfrage
• Artikelnummer: BYT-ORB3136266
• Hersteller Artikelnummer: orb3136266
• Alternativnummer: BYT-ORB3136266-10, BYT-ORB3136266-50
• Hersteller: Biorbyt
• Kategorie: Biochemikalien

Produktbeschreibung

VS1150 (Compound 11) is a phosphorylation-inducing chimeric small molecule (PHICS) designed to target BCR-ABL. It effectively hinders oncogenic kinase BCR-ABL signaling through inhibitory phosphorylation at the Y253 site (EC50: 69 nM), leading to apoptosis. Additionally, VS1150 can inhibit other oncogenic ABL fusion proteins and resistant mutants, such as T315I. This compound is applicable in research on chronic myeloid leukemia (CML) and other cancers driven by ABL fusion proteins.

Produkteigenschaften

• Molekulargewicht: 844.58
• CAS Nummer: [2855238-97-8]
• Formel: C36H38Cl4N12O4
• Target-Kategorie: Caspase,Bcr-Abl,PARP,STAT,ERK,Apoptosis