SMU-C68 is a highly selective small molecule agonist of the TLR1/2 heterodimer (EC50=0.009 µM). It activates the NF-kappaB and MAPK pathways, leading to the release of pro-inflammatory cytokines such as TNF-alpha and IL-1beta. SMU-C68 holds potential for cancer research applications.
Molekulargewicht:
411.54
CAS Nummer:
[2677039-75-5]
Formel:
C21H21N3O2S2
Target-Kategorie:
p38 MAPK,NF-kappaB,TLR
* Mehrwertsteuer und Versandkosten nicht enthalten. Irrtümer und Preisänderungen vorbehalten
