TRK-IN-32, CAS [[3044124-79-7]] Preis auf Anfrage

Produktübersicht

• Artikelname: TRK-IN-32, CAS [[3044124-79-7]] Preis auf Anfrage
• Artikelnummer: BYT-ORB3136626
• Hersteller Artikelnummer: orb3136626
• Alternativnummer: BYT-ORB3136626-10, BYT-ORB3136626-50
• Hersteller: Biorbyt
• Kategorie: Biochemikalien

Produktbeschreibung

TRK-IN-32 is a potent TRK inhibitor. It significantly suppresses TRKWT, TRKG595R, and TRKG667C with IC50 values of 0.08 nM, 2.14 nM, and 0.68 nM, respectively. Additionally, TRK-IN-32 exhibits antiproliferative activity against various Ba/F3 cell lines transformed by wild-type, xDFG mutant, solvent front, and gatekeeper mutant TRK fusion proteins. It also induces apoptosis in Ba/F3-TRKAWT and Ba/F3-TRKAG667C cells. TRK-IN-32 is applicable in research on various cancers, including thyroid cancer and secretory breast cancer.

Produkteigenschaften

• Molekulargewicht: 363.39
• CAS Nummer: [3044124-79-7]
• Formel: C19H18FN7
• Target-Kategorie: Trk receptor,Apoptosis