Rabbit polyclonal to HDAC1.Histone deacetylase 1 (HDAC1) is responsible for the deacetylation of lysine residues on the Nterminalpart of the core histones (H2A, H2B, H3 and H4). Histone deacetylation gives a tag forepigenetic repression and plays an important role in transcriptional regulation, cell cycle progressionand developmental events.