TGF beta 1 is a member of the larger TGF beta superfamily of cytokines produced by a wide variety of cells that are involved in the regulation of cell proliferation, differentiation, apoptosis, cellular homeostasis and a wide variety of other cellular functions. TGF beta 1 has been shown to regulate the actions of many other growth factors involved in a range of human diseases including renal disease, hepatic disease, heart failure and cardiomyopathies
