COX2/Cyclooxygenase 2 Rabbit pAb, Polyclonal
Artikelnummer:
EBT-EA024
- Bilder (1)
| Artikelname: | COX2/Cyclooxygenase 2 Rabbit pAb, Polyclonal |
| Artikelnummer: | EBT-EA024 |
| Hersteller Artikelnummer: | EA024 |
| Alternativnummer: | EBT-EA024-50, EBT-EA024-100 |
| Hersteller: | ELK Biotechnology |
| Wirt: | Rabbit |
| Kategorie: | Antikörper |
| Applikation: | IHC, WB |
| Spezies Reaktivität: | Human |
| Immunogen: | Synthetic Peptide |
| Alternative Synonym: | Cyclooxygenase 2, GRIPGHS, hCox 2, PGG/HS, PGH synthase 2, PGHS 2, PHS 2, PHS II, Prostaglandin G/H synthase 2, Prostaglandin H2 synthase 2, PTGS2 |
| Prostaglandin-endoperoxide synthase 2, also known as cyclooxygenase-2 or simply COX-2, is an enzyme that in humans is encoded by the PTGS2 gene. There are two isozymes of COX encoded by distinct gene products: a constitutive COX-1 (this enzyme) and an inducible COX-2, which differ in their regulation of expression and tissue distribution. The expression of these two transcripts is differentially regulated by relevant cytokines and growth factors. A splice variant of COX-1 termed COX-3 was identified in the CNS of dogs, but does not result in a functional protein in humans. Two smaller COX-1-derived proteins (the partial COX-1 proteins PCOX-1A and PCOX-1B) have also been discovered, but their precise roles are yet to be described. |
| Application Verdünnung: | WB 1:1,000 IHC 1:100 |

