COX2/Cyclooxygenase 2 Rabbit pAb, Polyclonal

Artikelnummer: EBT-EA024
Artikelname: COX2/Cyclooxygenase 2 Rabbit pAb, Polyclonal
Artikelnummer: EBT-EA024
Hersteller Artikelnummer: EA024
Alternativnummer: EBT-EA024-50, EBT-EA024-100
Hersteller: ELK Biotechnology
Wirt: Rabbit
Kategorie: Antikörper
Applikation: IHC, WB
Spezies Reaktivität: Human
Immunogen: Synthetic Peptide
Alternative Synonym: Cyclooxygenase 2, GRIPGHS, hCox 2, PGG/HS, PGH synthase 2, PGHS 2, PHS 2, PHS II, Prostaglandin G/H synthase 2, Prostaglandin H2 synthase 2, PTGS2
Prostaglandin-endoperoxide synthase 2, also known as cyclooxygenase-2 or simply COX-2, is an enzyme that in humans is encoded by the PTGS2 gene. There are two isozymes of COX encoded by distinct gene products: a constitutive COX-1 (this enzyme) and an inducible COX-2, which differ in their regulation of expression and tissue distribution. The expression of these two transcripts is differentially regulated by relevant cytokines and growth factors. A splice variant of COX-1 termed COX-3 was identified in the CNS of dogs, but does not result in a functional protein in humans. Two smaller COX-1-derived proteins (the partial COX-1 proteins PCOX-1A and PCOX-1B) have also been discovered, but their precise roles are yet to be described.
Klonalität: Polyclonal
Konzentration: 1mg/mL
Molekulargewicht: 70kDa
NCBI: 5743
UniProt: P35354
Application Verdünnung: WB 1:1,000 IHC 1:100
Western blot analysis of Hela with COX2 Rabbit Polyclonal antibody diluted at 1:1,000.