CD10 Rabbit pAb, Polyclonal

Produktübersicht

• Artikelname: CD10 Rabbit pAb, Polyclonal
• Artikelnummer: EBT-EA321
• Hersteller Artikelnummer: EA321
• Alternativnummer: EBT-EA321-50, EBT-EA321-100
• Hersteller: ELK Biotechnology
• Wirt: Rabbit
• Kategorie: Antikörper
• Applikation: IHC
• Spezies Reaktivität: Human, Mouse, Rat
• Immunogen: Recombinant Protein
• Alternative Synonym: CALLA, Enkephalinase,MME,NEP, Neutral endopeptidase antibody

Produktbeschreibung

CD10 is a zinc-dependent metalloprotease enzyme that degrades a number of small secreted peptides, most notably the amyloid beta peptide whose abnormal misfolding and aggregation in neural tissue has been implicated as a cause of Alzheimers disease. Synthesized as a membrane-bound protein, the neprilysin ectodomain is released into the extracellular domain after it has been transported from the Golgi apparatus to the cell surface. In neurons, neprilysin is regulated by the protein nicastrin, a component of the gamma secretase complex that performs a necessary step in processing amyloid precursor protein to amyloid beta.

Produkteigenschaften

• Klonalität: Polyclonal
• Konzentration: 1mg/mL
• Molekulargewicht: 85kDa
• NCBI: 4311
• UniProt: P08473

Anwendungsbeschreibung

• Application Verdünnung: IHC 1:200-500

Bilder

Immunohistochemical analysis of paraffin-embedded Human Kidney Tissue usingCD10(EA321)Rabbit pAb diluted at 1:500.