Recombinant 2019-nCoV NSP10 (N-6His)

Artikelnummer: EBT-EPT002
Artikelname: Recombinant 2019-nCoV NSP10 (N-6His)
Artikelnummer: EBT-EPT002
Hersteller Artikelnummer: EPT002
Alternativnummer: EBT-EPT002-50
Hersteller: ELK Biotechnology
Kategorie: Proteine/Peptide
Alternative Synonym: SARS-CoV 2 nsp10, SARS-CoV 2 Growth factor-like peptide, SARS-CoV 2 GFL
Recombinant 2019-nCoV NSP10 is produced by our E.coli expression system and the target gene encoding Ala1-Gln139 is expressed with a 6His tag at the N-terminus.
Molekulargewicht: Molecular weight: 17.9 KDa. Apparent molecular weight: 18 KDa, reducing conditions
UniProt: YP_009725306.1
Reinheit: Greater than 80% as determined by reducing SDS-PAGE.
Anwendungsbeschreibung: Background: Nsp10 have shown that it is a 15-kDa protein of unknown function that has been shown to interact with itself, nsp1, and nsp7. It colocalizes with N to sites of viral replication and is essential for replication. It plays a pivotal role in viral transcription by stimulating both nsp14 3-5 exoribonuclease and nsp16 2-O-methyltransferase activities. Therefore plays an essential role in viral mRNAs cap methylation. Nsp10 is a critical regulator of coronavirus RNA synthesis and may play an important role in polyprotein processing