Recombinant Human AREG

Produktübersicht

• Artikelname: Recombinant Human AREG
• Artikelnummer: EBT-EPT131
• Hersteller Artikelnummer: EPT131
• Alternativnummer: EBT-EPT131-10
• Hersteller: ELK Biotechnology
• Kategorie: Proteine/Peptide
• Alternative Synonym: Amphiregulin, AR, Colorectum Cell-Derived Growth Factor, CRDGF, AREG, SDGF, AREGB

Produktbeschreibung

Recombinant Human Amphiregulin is produced by our E.coli expression system and the target gene encoding Ser101-Lys198 is expressed.

Produkteigenschaften

• Molekulargewicht: Molecular weight: 11.4 KDa. Apparent molecular weight: 16 KDa, reducing conditions
• UniProt: P15514
• Reinheit: Greater than 95% as determined by reducing SDS-PAGE.

Anwendungsbeschreibung

• Anwendungsbeschreibung: Redissolve: Always centrifuge tubes before opening.Do not mix by vortex or pipetting. It is not recommended to reconstitute to a concentration less than 100µg/ml. Dissolve the lyophilized protein in distilled water. Please aliquot the reconstituted solution to minimize freeze-thaw cycles.. Endotoxin: Less than 0.1 ng/µg (1 EU/µg) as determined by LAL test. Background: Amphiregulin (AREG) is a single-pass membrane protein with 252 amino acids. AREG belongs to the amphiregulin family, which contains 1 EGF-like domain. AREG is expressed in a variety of tissues including ovary, placenta, lung, kidney, stomach, colon, and breast. It is related to Epidermal Growth Factor (EGF) and Transforming Growth Factor Alpha (TGF-alpha). As an EGF-related growth factor, AREG interacts with the EGF/TGF-alpha receptor to promote the growth of normal epithelial cells and inhibits the growth of certain aggressive carcinoma cell lines. AREG may also play a protective role in Bleomycin-Induced Pneumopathy