Recombinant Human VDB (C-6His)

Artikelnummer: EBT-EPT229
Artikelname: Recombinant Human VDB (C-6His)
Artikelnummer: EBT-EPT229
Hersteller Artikelnummer: EPT229
Alternativnummer: EBT-EPT229-10
Hersteller: ELK Biotechnology
Kategorie: Proteine/Peptide
Alternative Synonym: Vitamin D-Binding Protein, DBP, VDB, Gc-Globulin, Group-Specific Component, GC
Recombinant Human Vitamin D-Binding Protein is produced by our Mammalian expression system and the target gene encoding Leu17-Leu474 is expressed with a 6His tag at the C-terminus.
Molekulargewicht: Molecular weight: 52.3 KDa. Apparent molecular weight: 53 KDa, reducing conditions
UniProt: P02774
Reinheit: Greater than 95% as determined by reducing SDS-PAGE.
Anwendungsbeschreibung: Redissolve: Always centrifuge tubes before opening.Do not mix by vortex or pipetting. It is not recommended to reconstitute to a concentration less than 100µg/ml. Dissolve the lyophilized protein in distilled water. Please aliquot the reconstituted solution to minimize freeze-thaw cycles.. Endotoxin: Less than 0.1 ng/µg (1 EU/µg) as determined by LAL test. Background: Vitamin D-Binding Protein (DBP) is a member of the ALB/AFP/VDB family. DBP is a secreted protein and contains three albumin domains. The primary structure contains 28 cysteine residues forming multiple disulfide bonds. DBP acts as a multifunctional protein found in plasma, ascitic fluid, cerebrospinal fluid, and urine and on the surface of many cell types. DBP binds to vitamin D and its plasma metabolites and transports them to target tissues. DBP associates with membrane-bound immunoglobulin on the surface of B-lymphocytes and with IgG Fc receptor on the membranes of T-lymphocytes