Recombinant Human MetAP1D (N, C-6His)

Artikelnummer: EBT-EPT270
Artikelname: Recombinant Human MetAP1D (N, C-6His)
Artikelnummer: EBT-EPT270
Hersteller Artikelnummer: EPT270
Alternativnummer: EBT-EPT270-50
Hersteller: ELK Biotechnology
Kategorie: Proteine/Peptide
Alternative Synonym: Methionine Aminopeptidase 1D Mitochondrial, Methionyl Aminopeptidase Type 1D Mitochondrial, METAP1D, MAP1D
Recombinant Human Methionine Aminopeptidase 1D Mitochondrial is produced by our E.coli expression system and the target gene encoding Arg44-Ala335 is expressed with a 6His tag at the N-terminus, 6His tag at the C-terminus.
Molekulargewicht: Molecular weight: 35.4 KDa. Apparent molecular weight: 35-40 KDa, reducing conditions
UniProt: Q6UB28
Reinheit: Greater than 95% as determined by reducing SDS-PAGE.
Anwendungsbeschreibung: Endotoxin: Less than 0.1 ng/µg (1 EU/µg) as determined by LAL test. Background: Methionine Aminopeptidase 1D (METAP1D) is a mitochondrion protein that belongs to the peptidase M24A family. METAP1D is overexpressed at the protein level in colon cancer cell lines and colon tumors as compared to normal tissues. N-terminal methionine removal is an important cellular process required for proper biological activity, subcellular localization, and eventual degradation of many proteins. METAP1D is also active with zinc, manganese or divalent ions. It may also play an important role in colon tumorigenesis.