Cleaved-Plasma Kallikrein HC (R390) rabbit pAb, Rabbit, Polyclonal

Produktübersicht

• Artikelname: Cleaved-Plasma Kallikrein HC (R390) rabbit pAb, Rabbit, Polyclonal
• Artikelnummer: EBT-ES1072
• Hersteller Artikelnummer: ES1072
• Alternativnummer: EBT-ES1072-50, EBT-ES1072-100
• Hersteller: ELK Biotechnology
• Wirt: Rabbit
• Kategorie: Antikörper
• Applikation: ELISA, IF, IHC, WB
• Spezies Reaktivität: Human, Mouse, Rat
• Immunogen: The antiserum was produced against synthesized peptide derived from human KLKB1. AA range:341-390
• Alternative Synonym: KLKB1, KLK3, Plasma kallikrein, Fletcher factor, Kininogenin, Plasma prekallikrein

Produktbeschreibung

This gene encodes a glycoprotein that participates in the surface-dependent activation of blood coagulation, fibrinolysis, kinin generation and inflammation. The encoded preproprotein present in plasma as a non-covalent complex with high molecular weight kininogen undergoes proteolytic processing mediated by activated coagulation factor XII to generate a disulfide-linked, heterodimeric serine protease comprised of heavy and light chains. Certain mutations in this gene cause prekallikrein deficiency. Alternative splicing results in multiple transcript variants encoding different isoforms. [provided by RefSeq, Jan 2016],

Produkteigenschaften

• Klonalität: Polyclonal
• Konzentration: 1 mg/ml
• Molekulargewicht: 45kD
• NCBI: 3818
• UniProt: P03952

Anwendungsbeschreibung

• Application Verdünnung: Western Blot: 1/500 - 1/2000. Immunohistochemistry: 1/100 - 1/300. ELISA: 1/10000. Not yet tested in other applications.

Bilder

Western Blot analysis of various cells using Cleaved-Plasma Kallikrein HC (R390) Polyclonal Antibody diluted at 1:1000

Western Blot analysis of HeLa cells using Cleaved-Plasma Kallikrein HC (R390) Polyclonal Antibody diluted at 1:1000

Western blot analysis of lysates from HeLa cells, using KLKB1 (heavy chain,Cleaved-Arg390) Antibody. The lane on the right is blocked with the synthesized peptide.

Immunohistochemical analysis of paraffin-embedded human tonsil. 1, Antibody was diluted at 1:200(4 overnight). 2, Tris-EDTA,pH9.0 was used for antigen retrieval. 3,Secondary antibody was diluted at 1:200(room temperature, 30min).