p53 (Acetyl Lys372) rabbit pAb, Rabbit, Polyclonal

Produktübersicht

• Artikelname: p53 (Acetyl Lys372) rabbit pAb, Rabbit, Polyclonal
• Artikelnummer: EBT-ES1111
• Hersteller Artikelnummer: ES1111
• Alternativnummer: EBT-ES1111-50, EBT-ES1111-100
• Hersteller: ELK Biotechnology
• Wirt: Rabbit
• Kategorie: Antikörper
• Applikation: ELISA, IF, IHC, WB
• Spezies Reaktivität: Human, Mouse, Rat
• Immunogen: The antiserum was produced against synthesized Acetyl-peptide derived from human p53 around the Acetylation site of Lys372. AA range:331-380
• Alternative Synonym: TP53, P53, Cellular tumor antigen p53, Antigen NY-CO-13, Phosphoprotein p53, Tumor suppressor p53

Produktbeschreibung

tumor protein p53(TP53) Homo sapiens This gene encodes a tumor suppressor protein containing transcriptional activation, DNA binding, and oligomerization domains. The encoded protein responds to diverse cellular stresses to regulate expression of target genes, thereby inducing cell cycle arrest, apoptosis, senescence, DNA repair, or changes in metabolism. Mutations in this gene are associated with a variety of human cancers, including hereditary cancers such as Li-Fraumeni syndrome. Alternative splicing of this gene and the use of alternate promoters result in multiple transcript variants and isoforms. Additional isoforms have also been shown to result from the use of alternate translation initiation codons (PMIDs: 12032546, 20937277). [provided by RefSeq, Feb 2013],

Produkteigenschaften

• Klonalität: Polyclonal
• Konzentration: 1 mg/ml
• Molekulargewicht: 53kD
• NCBI: 7157
• UniProt: P04637

Anwendungsbeschreibung

• Application Verdünnung: Western Blot: 1/500 - 1/2000. IHC-p: 1:100-300 ELISA: 1/20000. Not yet tested in other applications.

Bilder

Western Blot analysis of Jurkat cells using Acetyl-p53 (K372) Polyclonal Antibody. Antibody was diluted at 1:2000. Secondary antibody(catalog:RS0002) was diluted at 1:20000

Western Blot analysis of 293T cells using Acetyl-p53 (K372) Polyclonal Antibody diluted at 1:2000. Secondary antibody(catalog:RS0002) was diluted at 1:20000

Immunohistochemical analysis of paraffin-embedded human-breast, antibody was diluted at 1:100

Western blot analysis of lysate from Jurkat cells, using p53 (Acetyl-Lys372) Antibody.